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The American Red Cross offers high-quality generic and specialty buffy coat products manufactured from healthy donor whole blood collections. These buffy coats are a good source of leukocytes for earlier stages of discovery and process development and can also be used in the manufacture of diagnostic products.
Generic buffy coats are manufactured from whole blood collected from a general blood donor. Corresponding donor demographic information on generic buffy coats is not available. Also, specific donor selection and donor recall ability for subsequent Leukopak product donations are not possible.
Generic buffy coats are shipped on the day of manufacture for next-day delivery. Units are packed and shipped per American Red Cross procedure, which allows for the client to select shipment at 1-6°C or 20-24°C.
Utilization of American Red Cross specialty buffy coats as starting material for your therapy, enables you to have access to raw material collected and processed in a consistent manner as you scale from discovery through commercialization, helping to minimize variability in starting material.
One key distinction between a buffy coat and peripheral blood mononuclear cells (PBMCs) is that the buffy coat contains both mononuclear (T cells, B cells, NK cells, dendritic cells and monocytes) and polymorphonuclear (granulocytes like neutrophils and eosinophils) white blood cells, while PBMCs contains only the mononuclear cell fraction. 2b1af7f3a8